Sunday, June 1, 2008

Prevention From Syphilis

This is an infection as old as the world. Although it is known by mankind for hundreds of years, it is still in people's lives, unfortunately. Ignorance and indifference has led to the Persistence of the disease sexually transmitted diseases. Syphilitic infection is of bacterial origin. Called Treponema pallidum bacteria produce. About this nasty infection, a few things. First, you should know that the most common way is transmission through sexual contact. Direct contact with the lesions, the infection during sexual contact is the main cause. It can also be used on other routes. Direct contact between a healthy individual and an infected person's saliva, the healthy person contracting the disease. Any contact with other bodily fluids such as seminal fluid, vaginal secretions of an infected person will definitely lead to infection. However, there is a nonsexual way the procurement of the disease, as reflected by biting, kissing, or through contaminated instruments or objects of any kind, the probability of transmission is high, as the statistics show that the risk of contamination, after having sexual contact with an infected person is as high as 30-50%. A single touch and the bacteria might be spreading. If we may say so, the debut of the disease is very "discreet" and it has a slow but certain evolution. If untreated, this terrible disease can have dramatic end of evolution. Today, the blood is tested before a blood transfusion of any kind This means that the risk of infection by blood transfusion should be zero. It never hurts to be extra careful, does it? Another means of transmission of syphilis from mother to newborn. In the event the pregnant woman is infected, it could transmit the bacteria their son or daughter. This type of pollution is a congenital transmission. As regards the manifestation of this disease is concerned, it materialized in more than one way, depending on the length of time that has passed since the exposure therefore contamination with the virus. There are many stages in the development of the disease, and it evolves from bad to worse along the years. The incubation period of the bacteria, covering the period after exposure to the infection, no clinical symptoms or biological rule. The incubation period can be up to ninety days in syphilitic infection. The secondary phase leads to the disappearance of symptoms initial phase, and it may take up to two years. During this period, the bacteria affects all of the human body fluids, including blood, vaginal secretions, seminal fluid, saliva, and the infected person is highly contagious for the other way around. To test the blood to reveal if there is an infection or not, contributes to the pursuit of the bacteria. The final diagnosis is made by microscopic analysis of the secretions from a primary or secondary lesion or other serological tests. Syphilis can be cured, as long as the treatment starts immediately after the exposure. Antibiotics are usually recommended, but when treatment begins when the disease has developed, it may cause permanent damage to the affected institutions.

Symptoms of Syphilis

Syphilis is a disease transmitted by a spirochaete bacterium, Treponema pallidum. Syphilis is a variety of presentations and can mimic many other infections and immune-mediated processes in advanced stages. Syphilis is passed from person to person by direct contact with a syphilis sore. Wound bodies occur, especially on the external genitalia, anus or rectum. Syphilis can also be passed from mother to child during pregnancy causes a disease called congenital syphilis. Any active person can be infected with syphilis, although there is a greater incidence among young people aged 15 to 30 years. It is more common in urban than rural areas. Syphilis can be frightening, because if it goes untreated, can lead to serious health problems and a person increase the risk of HIV, the human immunodeficiency virus that causes AIDS. Syphilis can be congenital or acquired. Primary syphilis occurs within 3 weeks after contact with an infected person. Syphilis has many alternative names, including syph, Cupid's Disease, the Pox, lues, and the French disease. The signs and symptoms of syphilis are countless; before the introduction of serological tests, the diagnosis was difficult, and the disease as the "Great Imitator" because it is so often confused with other diseases. Syphilis can not be spread through contact with toilet seats, doorknobs, swimming pools, whirlpools, bathtubs, shared clothes, food or utensils. The last stage of syphilis is known as tertiary syphilis and is characterized by brain or central nervous system involvement, cardiovascular involvement with inflammation of the aorta and gummatous syphilis. Untreated, syphilis can lead to serious complications or death. But with early diagnosis and treatment of disease can be treated successfully

Different names of Syphilis

"Syphilis" was coined by the Italian doctor and poet Girolamo Fracastoro in his epic poem to note, written in Latin with the title disease syphilis sive gallicus (Latin for "syphilis or the French disease") in 1530. The protagonist of the poem is a shepherd named Syphilus (perhaps a variant spelling Sipylus, a character in Ovid's Metamorphoses). Syphilus is considered the first person to contract the disease, by the god Apollo as a punishment for the disrespect that Syphilus and his followers had shown him. For this character Fracastoro derived a new name for the disease, he also in his medical text de Contagionibus ( "On infectious diseases). Until that time, such as notes Fracastoro, syphilis was the "French disease" in Italy and Germany, and the "Italian disease" in France. In addition, the Dutch called it the "Spanish disease," the Russians called it the "Polish disease", the Turks called it the "Christian disease" or "Frank's disease" (frengi) and the Tahitians called it the "British Disease ". This "national" names are often due to the disease in the current invasion of armies or sea crews, due to the high instance of unprotected sexual contact with prostitutes. It was also known as the "Great Smallpox" in the 16th Century distinguish it from smallpox. In its early stages, the Great pox a skin rash similar to smallpox (also known as variola). However, the name is misleading, as smallpox was a far more deadly disease. The terms "Lues (or venerea Lues, Latin for" sexually transmitted diseases fever ") and" Cupid's disease were also on syphilis. In Scotland, syphilis was the so-called Grand Gore. The ulcers suffered by British soldiers in Portugal was as "The Black Lion"

The History Of Syphilis

While working at the Rockefeller University (then the Rockefeller Institute for Medical Research) in 1913, Hideyo Noguchi, a Japanese scientist, showed the presence of the spirochete Treponema pallidum in the brain of a patient progressive paralysis that Treponema pallidum was the cause of the disease . Before the discovery Noguchi, syphilis was a burden for mankind in many countries, sometimes fehldiagnostiziert and often misattributed to political enemies. Some famous historical personalities, including Franz Schubert, Benjamin Keith Hamer, Hernando Cortez of Spain, Adolf Hitler, Benito Mussolini, and Ivan the Terrible, were alleged to have had syphilis. Guy de Maupassant and possibly Friedrich Nietzsche are thought to have been driven insane and finally killed by the disease. Al Capone contracted syphilis as a young man. By the time he was imprisoned in Alcatraz, reached his third stage, neurosyphilis, leaving him confused and disoriented. Syphilis led to the death of the artist Edouard Manet and artist Paul Gauguin is also said that victims of syphilis. Composers, also succumbed to syphilis Hugo Wolf, Frederick Delius, Scott Joplin and possibly Franz Schubert and Niccolò Paganini. The insanity caused by late-stage syphilis was once one of the most common forms of dementia, which was known as the paresis. One example is the suspicion of insanity of the established composers, Robert Schumann, although the exact cause of his death is still disputed by scientists. The Russian writer Leo Tolstoy suffered from syphilis during his youth, which was cured with arsenic treatment. A recent article in the European Journal of Neurology (June 2004) suggested that the founder of communism in Russia, Vladimir Ilyich Lenin, died of neurosyphilis. The rock critic Lester Bangs caught syphilis was healed and there was in his youth. Karen Blixen, the author of Out of Africa, contracted syphilis, while her husband live in Africa. He had contracted the disease from an African woman with whom he was unfaithful. After treatment in Denmark, she returned to Africa. Blixen was unable to have children

Definition of T.Pallidum

Treponema pallidum is a Gram-negative bacteria spirochaete. There are at least four well-known subspecies: T. pallidum pallidum, which causes syphilis; pertenue T. pallidum, which causes yaws; carateum T. pallidum, which causes pinta; endemicum and T. pallidum, which causes bejel. T. pallidum pallidum is a motile spirochaete that is usually acquired through close sexual contact, entering the host via violations in record epithelium or columnar epithelium. The organism can be switched to a fetus through transplacental passage during the later stages of pregnancy, the cause of congenital syphilis. The helical structure of T. pallidum pallidum allows for in a corkscrew motion by viscous media, such as mucus. It gains access to the host through blood and lymph tissues and mucous membranes. The subspecies causes yaws, Pinta, and bejel are morphologically and serologically not of T. pallidum pallidum (syphilis), but their transmission is not sexually transmitted diseases in the nature and course of each disease is significantly different. In the 17th July 1998 issue of the journal Science, a group of biologists reported how they sequenced the genomes of T. pallidum. The recent sequencing the genomes of several spirochetes provides a thorough analysis of the similarities and differences within these bacteria strain. Treponema pallidum subsp. pallidum is one of the smallest genomes of bacteria to 1.14 million base pairs (MB) and has limited metabolic capabilities, their adaptation by genome reduction to the rich environment of mammalian tissue. There is no vaccine against syphilis. The outer membrane of T. pallidum has too little surface proteins for an antibody to be effective. Efforts to develop a safe and effective vaccine syphilis have been hampered by the uncertainty about the relative importance of humoral and cellular mechanisms for protective immunity and the fact that T. pallidum outer membrane proteins were not clearly identified.